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The collaborative project F2F aims at conversion of fungal biomass to fine chemicals

F2F is funded with about 0.75 million € in the ZIM program of BMWi. The project is coordinated by WeissBioTech GmbH, who produce enzymes in fungal fermentations. Experts in chitin (Bruno Moerschbacher, Münster), bacterial consortia (Bodo Philipp, Münster), dipeptide production (Cysal GmbH) and metabolic engineering (Volker F. Wendisch, CeBiTec & Biology) are partners in F2F. The project partners met in Münster on June 29 to kick-off the project. F2F contributes to fostering the raw material change in chemical industry from petrol oil-based substrates to renewable resources. F2F aims at valorizing fungal biomass accumulating as waste during large scale fermentation processes to produce enzymes. Specifically, research focusses on developing a strategy to convert chitin, which is a component of fungal cell walls and a recalcitrant polymer made of glucosamine monomers with variable degree of acetylation, to dipeptides, diamines and amino acids. A pre-treatment process to extract chitin from fungal biomass will be developed. To enable access to chitin as alternative carbon substrate for fermentations, the approach involves metabolic engineering of chitin-hydrolyzing bacteria and producer strains as well as synthetic trophic interactions between them. Finally, a proof-of-principle of fermentative production of sought-after chemicals from fungal biomass shall be reached.

See further details on project-website http://www.f2f-zim.com


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